Case Study 2

A leading pharmaceutical company needed to manufacture 80kg of an active pharmaceutical intermediate using a Buchwald Hartwig amination reaction. The catalyst for this particular process would have cost $300,000. We identified alternative catalyst systems which reduced the catalyst cost of this process by more than $280,000. This case study demonstrates how the new catalyst system was identified by combining Design of Experiments (DoE) and Principal Component Analysis (PCA) in the development of catalytic reactions.

© Copyright Catalysis Consulting 2017 - All Rights Reserved. Paul Murray Catalysis Consulting - Company Registered in England - Number 08692613.